Purdue University-Main Campus · PharmacologyYeo Drug Delivery Lab
Yoon Yeo · West Lafayette, Indiana
Research Focus
Dr. Yoon Yeo's lab focuses on developing innovative drug delivery systems to treat eye diseases that cause blindness. They are particularly interested in repurposing the old antifungal drug griseofulvin to create long-acting formulations that can be injected into the eye for treating conditions like age-related macular degeneration. By using new polymer-based delivery methods, the lab aims to improve patient outcomes and convenience while reducing the cost of treatment.
ocular neovascularizationgriseofulvindrug deliverypolymeric implantseye diseasesangiogenesisrepurposing drugscontrolled release
Research Aims
3AIM 01Optimize the release kinetics of griseofulvin-encapsulated polymeric microparticles and implants.
AIM 02Evaluate the antiangiogenic effects of griseofulvin microparticles in animal models.
AIM 03Test the long-term drug release and efficacy of griseofulvin-releasing polymeric implants.
Skills the Lab Values
polymer formulationin vivo imagingdrug release kineticsintravitreal injectionsmouse modelsrabbit modelstoxicology assessmentcell culturemicroscopybiophysical characterization
Output against the department
Publications185top 48% of dept.221st of 462
this lab
most publishedleast published
Citations12ktop 33% of dept.153rd of 462
this lab
most citedleast cited
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