Oregon Health & Science University · PhysiologyOcular Pain and Sensitivity Lab
Sue A Aicher · Portland, Oregon
Research Focus
Dr. Sue A Aicher's lab focuses on understanding the mechanisms behind ocular pain and light sensitivity, especially in conditions like migraine and dry eye disease. The research involves studying how pain and light sensing in the eye are connected and how immune responses may influence these phenomena. By examining these interactions in rodent models, the lab aims to uncover potential new treatments for these common and distressing conditions.
ocular painphotophobiamigrainedry eye diseasetrigeminal nerveneural pathwaystherapeutic targetsrodent models
Research Aims
5AIM 01Investigate the role of trigeminal neurons in ocular pain and photophobia.
AIM 02Identify molecular mechanisms that contribute to pain sensitivity in migraine and dry eye disease.
AIM 03Examine interactions between pain-sensing neurons and light-sensing cells in the eye.
AIM 04Explore potential therapeutic targets to develop non-opioid pain treatments.
AIM 05Study the effects of immune cell infiltration on pain mechanisms in these conditions.
Skills the Lab Values
confocal microscopyelectrophysiologyimmunocytochemistrybehavioral testinganimal modelingneuroanatomical techniquesmolecular biology techniquesgene expression analysisproteomics
Output against the department
Publications149bottom 49% of dept.146th of 286
this lab
most publishedleast published
Citations4.9kbottom 42% of dept.165th of 286
this lab
most citedleast cited
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