Wayne State University · ChemistryThe GlycoInnovations Lab
Hien M Nguyen · Detroit, Michigan
Research Focus
Dr. Hien M Nguyen's lab at Wayne State University focuses on synthesizing complex carbohydrate structures to improve medical treatments and vaccines. They are actively developing new methods for creating glycosylations, which are crucial for producing compounds that can support cancer treatments and vaccine efficiency. The lab's research aims to better understand biologically important molecules and to enhance immune responses against diseases through innovative vaccine adjuvants.
glycosylationsaponinsvaccine adjuvantscarbohydrate synthesisglycosaminoglycanscancer therapy
Research Aims
5AIM 01Develop new methods for catalytic glycosylation to create complex carbohydrates.
AIM 02Synthesize and evaluate novel carbohydrate-based vaccine adjuvants.
AIM 03Investigate the biological roles of glycosaminoglycans in health and disease.
AIM 04Explore the potential of soyasaponins as safe and effective vaccine adjuvants.
AIM 05Create structurally defined libraries of heparan sulfate mimetics for biomedical research.
Skills the Lab Values
chemical synthesiscatalytic methodshigh pressure liquid chromatographyin vitro immunologyanalytical chemistrycell culture techniquesstructure elucidationimmunoassaysspectroscopy
Output against the department
Publications152bottom 37% of dept.137th of 216
this lab
most publishedleast published
Citations3.3kbottom 22% of dept.169th of 216
this lab
most citedleast cited
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