University of Pittsburgh-Pittsburgh Campus · BiologyExtracellular Vesicles and Cancer Outcomes Lab
Theresa L. Whiteside · Pittsburgh, Pennsylvania
Research Focus
Dr. Theresa L. Whiteside's lab at the University of Pittsburgh focuses on developing non-invasive biomarkers for patients with head and neck cancer. They study small extracellular vesicles (sEV), also known as exosomes, found in body fluids to help predict how patients will respond to therapies. By isolating and analyzing these vesicles from patient plasma, the lab aims to establish reliable indicators for prognosis and treatment effectiveness, potentially improving patient outcomes.
head and neck cancerextracellular vesiclesbiomarkerscancer therapyimmune suppression
Research Aims
3AIM 01Investigate the efficacy of immune capture methods for isolating sEV from patient plasma.
AIM 02Evaluate TEX and NTEX as biomarkers for cancer prognosis and response to therapy.
AIM 03Assess the role of TEX and NTEX in mediating immune suppression and their impact on treatment efficacy.
Skills the Lab Values
cell cultureplasma sample processingnanoflow cytometryhigh-resolution mass spectrometryimmunoassay development
Output against the department
Publications944top 2% of dept.17th of 1,033
this lab
most publishedleast published
Citations51ktop 5% of dept.50th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.