University of Pennsylvania · ChemistryThe Molecular Imaging Lab
Ivan Julian Dmochowski · Philadelphia, Pennsylvania
Research Focus
The Dmochowski Lab at the University of Pennsylvania focuses on developing innovative molecular probes for a variety of biomedical applications, particularly in cancer detection and imaging. The lab uses advanced techniques like MRI and FRET to study critical biological processes, such as cell metabolism and the delivery of therapeutic oligonucleotides. Students will have the opportunity to engage in cutting-edge research that has significant implications for human health and disease treatment.
molecular probescancer detectionMRIribose metabolismfluorescence resonance energy transferoligonucleotide therapeuticsxenon imaginganesthesiacell biologychemical biology
Research Aims
5AIM 01Develop novel xenon contrast agents for improved molecular imaging of lung cancer.
AIM 02Create a FRET-based sensor for real-time quantification of ribose levels in cells.
AIM 03Investigate ribose metabolic pathways to understand cell cycle dynamics.
AIM 04Enhance delivery mechanisms for therapeutic oligonucleotides in skeletal muscle.
AIM 05Explore xenon-protein interactions to improve anesthesia techniques.
Skills the Lab Values
cell culturefluorescence microscopymagnetic resonance imaging (MRI)small molecule designprotein engineeringreal-time imaging techniquesFRETRNA interferenceenzyme inhibition techniquesanalytical chemistry
Output against the department
Publications184bottom 44% of dept.121st of 216
this lab
most publishedleast published
Citations5.3kbottom 38% of dept.134th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.