Mercer University · PharmacologyCardiovascular Pharmacology Unit
Raquibul Hasan · Macon, Georgia
Research Focus
Dr. Raquibul Hasan's lab at Mercer University focuses on understanding how statins, widely used medications for heart disease, affect blood pressure. The research explores the mechanisms by which these drugs can lower blood pressure in some patients while having no effect in others. By studying different animal models, the lab aims to identify new therapeutic approaches that can help tailor treatments for individuals with both high blood pressure and cholesterol issues.
statinsblood pressure regulationvascular smooth musclehypertensioncGMPPDE1Avascular effectsendothelial dysfunctioncardiovascular diseasestherapeutic applications
Research Aims
5AIM 01Investigate the direct effects of statins on arterial contractility.
AIM 02Determine the mechanisms underpinning the blood pressure-lowering effects of statins.
AIM 03Characterize the role of the NO-PDE1A/cGMP-PKG signaling pathway.
AIM 04Study statin effects in both normotensive and hypertensive animal models.
AIM 05Propose new strategies for tailoring antihypertensive therapies for individual patients.
Skills the Lab Values
Western blottingcell culturemouse modelsmyographyconfocal imagingin silico analysispharmacologic experimentsdrug testingsignal transduction assaysexperimental design
Output against the department
Publications63bottom 12% of dept.407th of 462
this lab
most publishedleast published
Citations880bottom 3% of dept.448th of 462
this lab
most citedleast cited
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