University of California-San Francisco · PharmacologyAdipose Tissue Engineering Lab
Nadav Ahituv · San Francisco, California
Research Focus
Dr. Nadav Ahituv's lab focuses on using adipose tissues (body fat) to develop innovative cancer therapies. By bioengineering fat cells to mimic brown adipose tissue, which is more effective in utilizing glucose and fat, they aim to suppress tumor growth. The lab's research is groundbreaking because it explores using engineered adipocytes (fat cells) as a form of cellular therapy to combat various types of cancer.
adipose tissuecancer therapyCRISPRbioengineeringtumor growthbreast canceradipocytescellular therapyfat metabolismglucose utilization
Research Aims
3AIM 01Engineer adipocytes and organoids to enhance glucose and fat utilization for tumor suppression.
AIM 02Test the therapeutic effects of CRISPRa engineered adipocytes in various cancer cell models.
AIM 03Investigate the potential of adipocyte engineering using patient-derived tissues for personalized cancer treatment.
Skills the Lab Values
CRISPR activationcell culture techniquesmouse modelsco-culture techniquestissue engineeringadipose organoid developmentgene expression analysisbiological assaysflow cytometrysurgical tissue engineering
Output against the department
Publications416top 15% of dept.70th of 462
this lab
most publishedleast published
Citations16ktop 24% of dept.113th of 462
this lab
most citedleast cited
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