University of Massachusetts-Amherst · Biomedical EngineeringHIV Detection Innovations Lab
Chang Liu · Amherst, Massachusetts
Research Focus
Dr. Chang Liu's lab at the University of Massachusetts Amherst focuses on innovative technologies for improving HIV detection and prevention. The team is developing a new self-test device that allows individuals to conduct HIV tests using just a drop of blood from their finger. This is designed to enhance early detection of infections and help monitor therapy effectiveness in a user-friendly way, potentially transforming HIV testing into an accessible, at-home process.
HIV self-testingnanopore technologymicrofluidicsultrasensitive detectionp24 antigenhealthcare technologiesclick chemistry
Research Aims
5AIM 01Develop a self-testing device for quantifying HIV-1 p24 antigen from finger prick blood.
AIM 02Establish a reliable method to detect acute HIV infections at home.
AIM 03Evaluate the usability and acceptability of the self-testing device in clinical settings.
AIM 04Correlate p24 antigen detection with viral load to monitor treatment adherence.
AIM 05Improve accessibility to HIV testing to enhance public health outcomes.
Skills the Lab Values
microfluidicsnanopore sequencingclick chemistryblood sample preparationdevice prototypingdiagnostic test developmentclinical trial evaluationdata collectionbiological assays
Output against the department
Publications575top 12% of dept.72nd of 595
this lab
most publishedleast published
Citations30ktop 10% of dept.58th of 595
this lab
most citedleast cited
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