Icahn School of Medicine at Mount Sinai · NeuroscienceGut-Brain Connection Lab
Ivan E De Araujo · New York, New York
Research Focus
Dr. Ivan E De Araujo's lab at the Icahn School of Medicine focuses on understanding how the brain and gut communicate through specific spinal pathways. This research is important for uncovering how these connections affect emotional and cognitive functions, particularly in relation to disorders such as depression, anxiety, and other gastrointestinal issues. By studying the circuitries involved in gut sensations, the lab aims to identify potential new treatments for these conditions.
gut-brain axisspinal sensory pathwaysinteroceptionemotional processingcognitive functionneural circuitrygastrointestinal motilityreward behavior
Research Aims
5AIM 01Map the spinal sensory pathways that communicate gut sensations to the brain.
AIM 02Investigate the impact of gastric stimuli on brain function.
AIM 03Identify the neural circuitries involved in emotional and cognitive responses to gut signals.
AIM 04Explore potential therapeutic targets for gastrointestinal-related psychological disorders.
AIM 05Develop methodologies for studying gut-brain communication in awake mice.
Skills the Lab Values
optogeneticsin vivo electrophysiologyviral injectionswhole-brain imagingc-Fos mappinglight-sheet microscopyanimal behavioral assayscomputer-operated intraluminal distensionneuroscience research methods
Output against the department
Publications97bottom 32% of dept.455th of 671
this lab
most publishedleast published
Citations10ktop 39% of dept.264th of 671
this lab
most citedleast cited
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