UWMUniversity of Wisconsin-Madison · Biochemistry
Cryptococcus Research Unit
Christina M Hull · Madison, Wisconsin
Research Focus
Dr. Christina M Hull's lab at the University of Wisconsin-Madison focuses on understanding the biology of Cryptococcus, a fungus that causes serious diseases, especially in people with weakened immune systems. The lab studies how Cryptococcus spores germinate and grow, aiming to uncover new ways to develop antifungal treatments. By exploring the interactions between these fungal spores and the human immune system, the research seeks to identify potential therapeutic targets that could help prevent or treat lethal fungal infections.
Cryptococcusfungal pathogenesisspore germinationimmunocompromised diseasesantifungal therapeutics
Research Aims
3AIM 01Determine the molecular pathways required for spore germination.
AIM 02Identify the processes that promote germination competence of spores.
AIM 03Examine how spore germination affects host-pathogen interactions and disease progression.
Skills the Lab Values
molecular geneticsgene expression analysiscell culture techniquesin vitro tissue culturemouse models of infectionquantitative germination assayschemical geneticsprotein composition analysispathogen-host interaction studies
Output against the department
Publications81bottom 17% of dept.334th of 402
this lab
most publishedleast published
Citations3.9kbottom 21% of dept.316th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.