Harvard University · BiologyRegehr Lab
Wade G Regehr · Cambridge, Massachusetts
Research Focus
Dr. Wade G. Regehr's lab at Harvard Medical School studies the complex circuitry of the cerebellum, focusing on how different types of neurons contribute to its functions. The lab examines how these neurons process signals and influence behaviors, such as motor control and social interactions. By upgrading our understanding of cerebellar circuits, the research aims to shed light on cerebellar disorders and their effects on neurological health.
cerebellar circuitsneuron subtypeselectrophysiologyoptogeneticsbehavioral assaysmotor controlsocial behaviorcognitionmouse geneticscircuit reconstruction
Research Aims
5AIM 01Investigate the contribution of different cerebellar neuron subtypes to signal processing.
AIM 02Examine the regional specialization of cerebellar circuitry in relation to diverse behaviors.
AIM 03Utilize intersectional mouse genetics to target specific cerebellar cell types.
AIM 04Combine electrophysiological and optogenetic methods to analyze cerebellar connectivity.
AIM 05Develop computational models to enhance understanding of cerebellar functions and disorders.
Skills the Lab Values
electrophysiologyoptogeneticsmouse modelsbehavioral testingserial electron microscopycircuit reconstructiondata analysis in neurosciencemultielectrode recordingsgenetic manipulationcomputer modeling
Output against the department
Publications204top 32% of dept.331st of 1,033
this lab
most publishedleast published
Citations26ktop 14% of dept.144th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.