New York University · Microbiology & ImmunologyLung Immunity and Macrophage Dynamics Lab
Kamal Mohan Khanna · New York, New York
Research Focus
Dr. Kamal Mohan Khanna's lab focuses on the role of different macrophage populations in the lung and their functions during immune responses. The research explores how factors like obesity and diabetes can alter these immune responses, especially in the context of respiratory viral infections like COVID-19 and influenza. By understanding how these macrophages operate and adapt, the lab aims to develop new therapeutic strategies for improving immune function in affected individuals.
macrophagestype 2 immune responseobesitydiabetesviral infectionslung immunitytrained immunityinflammation
Research Aims
5AIM 01Investigate the role of resident macrophages in regulating type 2 immune responses.
AIM 02Examine how obesity and diabetes alter pulmonary immune responses to respiratory viruses.
AIM 03Identify the distinct functions of different macrophage subsets in lung tissues.
AIM 04Explore the mechanisms behind trained immunity in lung macrophages post-infection.
AIM 05Develop therapeutic targets to enhance immune responses in individuals with chronic diseases.
Skills the Lab Values
cell culturemouse modelsflow cytometryRNA sequencingconfocal microscopyspatial transcriptomicsimmunohistochemistryepigenetic analysis
Output against the department
Publications149top 44% of dept.214th of 486
this lab
most publishedleast published
Citations7.3ktop 48% of dept.234th of 486
this lab
most citedleast cited
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