Rutgers University-New Brunswick · PharmacologyRoth Virology Lab
Monica J. Roth · New Brunswick, New Jersey
Research Focus
Dr. Monica J. Roth's lab focuses on understanding how retroviruses interact with host cell receptors, which is crucial for developing new antiviral drugs. By utilizing advanced computational modeling and protein structure prediction techniques, the lab aims to identify novel viral proteins and their binding partners in host cells. This research has significant implications for tackling viral diseases and cancer by exploring new strategies for drug design and therapeutic interventions.
retroviral proteinsviral receptorsdrug designmolecular modelingstructural biology
Research Aims
5AIM 01Identify novel retroviral Env proteins that interact with host receptors.
AIM 02Study the binding affinities of retroviral proteins to host proteins.
AIM 03Develop small molecule inhibitors targeting specific viral-host interactions.
AIM 04Utilize AI-driven modeling tools to enhance protein interaction design.
AIM 05Explore the implications of viral pathogenesis on public health.
Skills the Lab Values
protein structure predictioncomputer-aided drug discoveryNMR structural studiesbioinformaticscell physiology
Output against the department
Publications121bottom 34% of dept.303rd of 462
this lab
most publishedleast published
Citations3.0kbottom 23% of dept.358th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.