George Washington University · Microbiology & ImmunologyMaggirwar Immunology Lab
Sanjay B. Maggirwar · Washington, District of Columbia
Research Focus
Dr. Sanjay B. Maggirwar's lab at George Washington University focuses on understanding how platelets contribute to the persistence of HIV infections, particularly in the brain. The research investigates viral reservoirs in the central nervous system of people living with HIV, aiming to develop strategies to eliminate these reservoirs. By studying SIV-infected rhesus macaques, the lab explores the complex interactions between the immune system and HIV, which could be crucial for finding a cure.
HIVviral reservoirsCNSplateletsSIVneuroinflammationHIV persistenceimmunologydrug developmentmonocytes
Research Aims
3AIM 01Investigate the role of platelet-mediated changes in monocytes during acute HIV infection.
AIM 02Assess how disruption of platelet formation affects viral persistence in the CNS.
AIM 03Examine the relationship between platelets, viral rebound, and neuroinflammation after stopping ART.
Skills the Lab Values
animal modelsin vivo experimentationpharmacologic interventionscell cultureimmunological assaysneuroinflammation analysisviral load measurementbiostatisticsflow cytometrymicroscopy
Output against the department
Publications149top 44% of dept.213th of 486
this lab
most publishedleast published
Citations6.3kbottom 46% of dept.263rd of 486
this lab
most citedleast cited
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