EUEmory University · Microbiology & Immunology
Treg Dynamics Lab
Chaoran Li · Atlanta, Georgia
Research Focus
Dr. Chaoran Li's lab at Emory University focuses on understanding how specialized immune cells called regulatory T cells (Tregs) function in the skin. These Tregs help prevent skin inflammation and maintain tissue health. The lab explores the metabolic processes and epigenetic changes that influence these immune cells, particularly in response to environmental factors. Their goal is to develop new therapeutic strategies to treat inflammatory skin diseases like psoriasis and atopic dermatitis.
skin Tregsmetabolismepigenetic regulationinflammatory skin diseasesCRISPR/Cas9
Research Aims
5AIM 01Understand the metabolic requirements of skin Tregs.
AIM 02Dissect how glycolysis supports skin Treg homeostasis.
AIM 03Investigate the role of hypoxia in skin Treg function.
AIM 04Elucidate the epigenetic changes in skin Tregs during inflammation.
AIM 05Explore therapeutic strategies to target skin Tregs for inflammatory skin diseases.
Skills the Lab Values
single-cell metabolic profilingCRISPR/Cas9 gene editingATAC-seqCUT&Tagcell culture
Output against the department
Publications206top 31% of dept.151st of 486
this lab
most publishedleast published
Citations4.4kbottom 34% of dept.319th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.