University of Iowa · NeuroscienceHypertension and Neuro Regulation Lab
Kamal Rahmouni · Iowa City, Iowa
Research Focus
Dr. Kamal Rahmouni's lab focuses on understanding the mechanisms behind hypertension, particularly how the brain regulates blood pressure under different conditions like obesity. They study unique structures in neurons called primary cilia, and how these cilia may contribute to high blood pressure and fluid balance. The lab uses advanced technologies to observe and manipulate brain neuron activity to gain insights into hypertension, aiming to develop new treatment strategies for cardiovascular diseases.
hypertensionneural regulationobesityblood pressuresympathetic nervous system
Research Aims
5AIM 01Investigate the role of neuronal primary cilia in regulating hypertension.
AIM 02Evaluate the impact of specific neuronal manipulations on blood pressure control.
AIM 03Explore the relationship between obesity, FGF21 hormone, and blood pressure regulation.
AIM 04Assess how neuronal signaling alters sympathetic nerve activity in hypertensive conditions.
AIM 05Identify new therapeutic targets for treating hypertension related to obesity.
Skills the Lab Values
mouse modelsoptogeneticschemogeneticsphysiological phenotypingneuroimagingcell culturemolecular biology techniquesdata analysis using softwareexperimental design and executiongenetic engineering
Output against the department
Publications395top 16% of dept.105th of 671
this lab
most publishedleast published
Citations18ktop 23% of dept.157th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.