Dartmouth College · Microbiology & ImmunologyTissue Immunity and Cancer Group
Yina Hsing Huang · Hanover, New Hampshire
Research Focus
Dr. Yina Hsing Huang's research lab focuses on understanding how certain immune cells, particularly tissue-resident memory T cells, can be sustained and made effective against cancer. The lab investigates innovative strategies for enhancing chimeric antigen receptor (CAR) T cell therapies, which show promise in treating solid tumors by overcoming the immune suppression created by the tumor environment. Their work aims to develop better long-lasting immune responses that can protect individuals from cancer recurrence.
Tissue Resident Memory T cellsChimeric Antigen Receptor (CAR) T cellsCancer ImmunotherapyTumor MicroenvironmentMelanomaCell Signaling
Research Aims
3AIM 01Examine how tissue-resident memory T cells persist and function in cancer.
AIM 02Investigate the mechanisms of CAR T cell effectiveness in solid tumors.
AIM 03Analyze the impact of myeloid cells on the retention of memory T cells in tissues.
Skills the Lab Values
Flow CytometryMouse ModelsImmunofluorescent ImagingCell CultureGene Editing (CRISPR)Cytometric AnalysisRNA SequencingData AnalysisProtein Analysis (Western Blot)
Output against the department
Publications131top 50% of dept.242nd of 486
this lab
most publishedleast published
Citations2.5kbottom 15% of dept.412th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.