University at Buffalo · ChemistryThe PFAS Exposure Research Lab
Gunes Ekin Atilla-Gokcumen · Buffalo, New York
Research Focus
Dr. Gunes Ekin Atilla-Gokcumen's lab focuses on understanding the health risks associated with per- and polyfluoroalkyl substances (PFAS), a group of chemicals that contaminate our environment and affect human health. The lab investigates how PFAS exposure impacts brain development and function, particularly in relation to neurodevelopmental disorders like autism and ADHD. They use zebrafish models and various experimental techniques to uncover the cellular mechanisms of PFAS uptake and its neurotoxic effects.
PFASneurotoxicityneurodevelopmentautismADHDbioaccumulationzebrafish modelscellular uptaketransport proteinshealth risks
Research Aims
3AIM 01Define the chemical interactions that mediate neuronal uptake of PFAS
AIM 02Elucidate the neurotoxic effects of PFAS in vitro and in vivo
AIM 03Assess impacts of PFAS on neurodevelopment and behavior using zebrafish models
Skills the Lab Values
cell culturegene expression analysiszebrafish assaysmolecular dynamics simulationsphenotypic assaysimmunohistochemistryexperimental designcomputational modelingtoxicity testingbioinformatics
Output against the department
Publications125bottom 28% of dept.155th of 216
this lab
most publishedleast published
Citations3.4kbottom 25% of dept.163rd of 216
this lab
most citedleast cited
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