MCWMedical College of Wisconsin · Biology
Placental Health Research Lab
Rashmi Sood · Milwaukee, Wisconsin
Research Focus
Dr. Rashmi Sood's lab studies placental abruption, a serious pregnancy complication that occurs when the placenta separates from the uterus before delivery. The lab focuses on understanding the interplay between blood clotting and inflammation in this condition, using mouse models to investigate how specific immune cells and molecular processes contribute to placental damage. The ultimate goal is to identify potential therapeutic targets that could help prevent this dangerous complication in pregnancy.
placental abruptioncoagulation-inflammation crosstalkthrombin receptorinflammatory responseneutrophilsimmune cell traffickingoxidative stresspregnancy complicationsmaternal thrombophilia
Research Aims
3AIM 01Identify and phenotype altered immune cell populations in the decidua during placental abruption.
AIM 02Dissect the roles of coagulation components and vascular endothelium in placental abruption.
AIM 03Determine the mediators of inflammation and oxidative stress in the pathogenesis of placental abruption.
Skills the Lab Values
mouse modelsflow cytometrycell cultureimmunohistochemistryPCRhistone modification analysisinflammatory cytokine assaystissue processinggenetic knockout techniques
Output against the department
Publications47bottom 11% of dept.924th of 1,033
this lab
most publishedleast published
Citations1.6kbottom 11% of dept.922nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.