Albany Medical College · Microbiology & Immunology

Vesicle Defense Lab

Wei Sun · Albany, New York

Research Focus

Dr. Wei Sun's lab at Albany Medical College focuses on creating innovative vaccines to fight against plague, a serious infectious disease caused by Yersinia pestis. The lab is particularly interested in developing Yersinia outer-membrane vesicle vaccines to offer more effective protection than current options. By studying how these vesicles can stimulate the immune system, they aim to contribute significantly to public health by addressing the threat of plague, especially in cases of drug-resistant strains.

plagueYersinia pestisvaccine developmentouter-membrane vesiclesimmune response

Research Aims

AIM 01Develop acellular vaccines using outer-membrane vesicles from Yersinia pseudotuberculosis.

AIM 02Evaluate the effectiveness of these vaccines in rodent models.

AIM 03Investigate the immune mechanisms activated by the vaccine to inform future developments.

Skills the Lab Values

bacterial cultureimmunological assaysanimal modelsvaccine formulationflow cytometry

Vesicle Defense Lab

Research Focus

Research Aims

Skills the Lab Values

Output against the department