New York University · NeuroscienceBasu Lab
Jayeeta Basu · New York, New York
Research Focus
Dr. Jayeeta Basu's lab at NYU School of Medicine focuses on understanding the brain circuits involved in memory and how they are affected by Alzheimer's disease (AD). By studying specific types of inhibitory neurons in the hippocampus and entorhinal cortex, the lab aims to identify new therapeutic targets to improve memory function in patients suffering from early stages of AD. The research combines advanced techniques in neuroscience, including imaging and electrophysiology, to explore the resilience and vulnerability of these circuits in both animal models and human brain samples.
Alzheimer's diseasememory impairmentGABAergic circuitsneural plasticityneuromodulationinterneuronselectrophysiologyproteomicsmouse modelscognition
Research Aims
3AIM 01Investigate GABAergic microcircuits in the hippocampus related to memory deficits in Alzheimer's disease.
AIM 02Evaluate the impact of neuromodulation on memory-guided behavior in AD mouse models.
AIM 03Assess the structural integrity of specific inhibitory neurons in human post-mortem brain tissue from AD patients.
Skills the Lab Values
in vivo two-photon imagingoptogeneticselectrophysiologyimmunohistochemistrymouse behavioral assaysdata analysisproteomic techniquescell cultureanimal surgerysignal processing
Output against the department
Publications41bottom 7% of dept.619th of 671
this lab
most publishedleast published
Citations2.1kbottom 13% of dept.583rd of 671
this lab
most citedleast cited
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