University of Toledo · PhysiologyParuchuri Inflammation Lab
Sailaja Paruchuri · Toledo, Ohio
Research Focus
Dr. Sailaja Paruchuri's lab at the University of Toledo focuses on understanding how specific receptors in lung cells influence inflammation, particularly in conditions like asthma and acute lung injury. The lab investigates the role of cysteinyl leukotriene receptors and their impact on macrophage behavior, which are essential immune cells in the body. By studying these mechanisms, the lab aims to develop new therapeutic strategies for treating lung inflammation and related diseases.
lung inflammationmacrophagescysteinyl leukotriene receptorsasthmaacute lung injury
Research Aims
3AIM 01Investigate the role of CysLT1R in modulating macrophage inflammatory responses.
AIM 02Analyze how CysLT1R influences immune cell activity in lung inflammation.
AIM 03Explore the therapeutic effects of blocking CysLT1R in acute lung injury models.
Skills the Lab Values
cell culturemolecular biology techniquesanimal modelsin vitro experimentationimmunohistochemistry
Output against the department
Publications150top 50% of dept.143rd of 286
this lab
most publishedleast published
Citations3.9kbottom 31% of dept.196th of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.