Dartmouth College · Microbiology & ImmunologyTurk Lab
Mary Jo Turk · Hanover, New Hampshire
Research Focus
Dr. Mary Jo Turk's lab at Dartmouth College focuses on understanding how a specific type of immune cell, called tissue resident memory T cells, functions in fighting cancer. Their research looks at how these cells are generated, how they move within the body, and their role in preventing cancer recurrence and spread. By studying both mice and human patients, the lab aims to develop strategies to enhance tumor immunity, potentially leading to better cancer treatments.
T cell immunitytissue resident memory T cellscancer immunotherapymelanomanon-small cell lung cancerimmune cell traffickinginterferon signalingmetastasis prevention
Research Aims
3AIM 01Define the mechanisms of type-1 interferon production critical for T cell programming.
AIM 02Investigate the dynamics of tissue resident memory T cells between skin and lymph nodes.
AIM 03Characterize the function and significance of lymph node T cell populations in cancer patients.
Skills the Lab Values
flow cytometrycell culturemouse modelsimmunohistochemistryRNA sequencingT cell isolationcytokine profilingimmunofluorescenceanimal surgery
Output against the department
Publications188top 35% of dept.169th of 486
this lab
most publishedleast published
Citations7.4ktop 47% of dept.230th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.