Johns Hopkins University · BiologyCell Migration and Membrane Dynamics Lab
Takanari Inoue · Baltimore, Maryland
Research Focus
Dr. Takanari Inoue's lab at Johns Hopkins University studies how cells move and migrate, which is vital for processes like wound healing and how diseases like cancer spread. They focus on the physical characteristics of cell membranes and their interactions with signaling molecules that guide cell movement. By developing specialized molecular tools, the lab aims to understand the complex relationship between cell migration, signaling, and the properties of membranes.
chemotaxiscell migrationmembrane dynamicsactin cytoskeletonmolecular actuatorssignal transductionfilopodialamellipodiadisease progressionbiomolecular condensates
Research Aims
5AIM 01Investigate how membrane curvature affects cell migration.
AIM 02Explore the interaction between signal transduction and membrane mechanics in migrating cells.
AIM 03Characterize the role of phase-separated biomolecular condensates in cell movement.
AIM 04Determine the molecular mechanisms driving filopodia and lamellipodia formation.
AIM 05Quantify the response of signaling components to membrane deformation.
Skills the Lab Values
molecular actuator developmentcell culturelive-cell imagingmicroscopyactin assaysmembrane manipulationphase separation techniquessignaling pathway analysisprotein interactionsquantitative analysis
Output against the department
Publications137bottom 49% of dept.521st of 1,033
this lab
most publishedleast published
Citations7.5ktop 49% of dept.508th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.