University of South Carolina-Columbia · ChemistryLu Homeostasis Lab
Qun Lu · Columbia, South Carolina
Research Focus
Dr. Qun Lu's lab at the University of South Carolina focuses on understanding and developing new therapeutic strategies for chronic diseases like Alzheimer's and ALS. By restoring the natural balance of specific signaling pathways in the brain, instead of simply stimulating or inhibiting them, they aim to create innovative treatments that could alter the course of these diseases. Their research could lead to breakthroughs in how we address slow progression disorders overall, providing insights that might be applied to other complex health issues.
homeostasisAlzheimer's diseaseALSGTPase signalingchronic diseasesdrug developmentneurodegenerative disorderstherapeutic strategies
Research Aims
4AIM 01Investigate the role of small GTPases in Alzheimer's disease and ALS.
AIM 02Develop dual function small molecules to restore signaling balance.
AIM 03Test the effects of signaling modulation in mouse models of disease.
AIM 04Establish new therapeutic paradigms for chronic disease treatment.
Skills the Lab Values
cell culturemouse modelssmall molecule designprotein analysissignal transduction pathwayspharmacologybehavioral assaysbiochemical assays
Output against the department
Publications113bottom 24% of dept.165th of 216
this lab
most publishedleast published
Citations4.5kbottom 33% of dept.144th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.