Augusta University · BiologyThe Transport Dynamics Lab
Stephen Tymanskyj · Augusta, Georgia
Research Focus
Dr. Stephen Tymanskyj's lab at Augusta University focuses on understanding how intracellular transport works in neurons, especially in relation to neurodevelopmental and neurodegenerative diseases. The team is developing a novel optogenetic method that uses artificially created cargo to study motor proteins and their role in transporting materials within neurons. This research aims to uncover the fundamental mechanisms of transport processes and how they are affected by genetic mutations linked to disorders like autism and Parkinson's disease.
intracellular transportneurodevelopmental disordersneurodegenerative diseasesoptogeneticsmotor proteinskinesinsaxon growthcell biology
Research Aims
4AIM 01Develop an optogenetic system to study intracellular transport in neurons.
AIM 02Create artificial cargo for probing motor protein functions without interference from endogenous proteins.
AIM 03Investigate how mutations in motors affect their function and contribute to neurological diseases.
AIM 04Assess the spatial and temporal dynamics of cargo transport within neurons.
Skills the Lab Values
optogeneticscell culturemicroscopymolecular cloningneuron imagingWestern blotRNA isolationprotein purification
Output against the department
Publications20bottom 2% of dept.1,008th of 1,033
this lab
most publishedleast published
Citations450bottom 2% of dept.1,016th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.