University at Buffalo · EngineeringBiodegradable Drug Delivery Innovations Lab
Chong Cheng · Buffalo, New York
Research Focus
Chong Cheng's lab focuses on developing innovative drug delivery systems that are biodegradable and do not use polyethylene glycol (PEG), which can cause immune reactions. The team is creating novel zwitterionic polymer-drug conjugates (ZPDCs) that can effectively deliver multiple drugs, specifically targeting pancreatic cancer treatment. Their research combines chemistry and engineering to improve the safety and efficacy of drug therapies, contributing to better clinical outcomes for patients.
biodegradable polymersdrug deliveryzwitterionic polymersmultidrug co-deliverypolymer-drug conjugatescancer therapybiocompatibilitybiochemical interactions
Research Aims
3AIM 01Develop biodegradable zwitterionic polymer-drug conjugates for drug delivery.
AIM 02Investigate the structure-dependent interactions of ZPDCs with biological environments.
AIM 03Evaluate the in vivo behaviors and effectiveness of ZPDCs in cancer treatment.
Skills the Lab Values
polymer synthesisdrug formulationcell culturein vivo studiesbiochemical assaysmicroscopydrug release kineticsflow cytometrypharmacokinetics
Output against the department
Publications392top 18% of dept.50th of 278
this lab
most publishedleast published
Citations19ktop 21% of dept.57th of 278
this lab
most citedleast cited
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