Pennsylvania State University-Main Campus · NeuroscienceArnold Lab
Amy Christine Arnold · University Park, Pennsylvania
Research Focus
Dr. Amy Christine Arnold's lab at Penn State Hershey focuses on understanding the relationship between obesity and hypertension, particularly how a protective hormone called angiotensin-(1-7) can improve cardiovascular health in obese individuals. They explore both cellular mechanisms and clinical outcomes related to blood pressure and metabolic function to develop better therapies. This research is vital as obesity-related hypertension is a growing global health issue.
angiotensin-(1-7)hypertensionobesityendothelial functioninsulin sensitivitycardiovascular healthmetabolic disorderssympathetic activityclinical studies
Research Aims
5AIM 01Investigate how angiotensin-(1-7) affects blood pressure in obese hypertensive individuals.
AIM 02Examine the impact of angiotensin-(1-7) on endothelial function and insulin sensitivity.
AIM 03Assess sympathetic activity changes in response to angiotensin-(1-7) treatment.
AIM 04Conduct mechanistic studies to understand the role of angiotensin-(1-7) in cardiovascular health.
AIM 05Explore the effects of angiotensin-(1-7) in patients with pure autonomic failure.
Skills the Lab Values
clinical trial designintravenous infusionanimal models endothelial function assessmentblood pressure measurementmetabolic profilingglucose clamp techniquesstatistical analysisdata management
Output against the department
Publications183top 41% of dept.275th of 671
this lab
most publishedleast published
Citations3.7kbottom 27% of dept.487th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.