University of Illinois Chicago · BiochemistryRehman Lab
Jalees Rehman · Chicago, Illinois
Research Focus
Dr. Jalees Rehman's lab at the University of Illinois at Chicago focuses on understanding the interactions between pathogens and the immune system, particularly in the context of diseases like Alzheimer's and lung injuries. The lab investigates how infections can lead to cellular aging and inflammation, impacts on the blood-brain barrier in Alzheimer's patients, and utilizes advanced human organoid models to study lung disease and repair mechanisms. Their work aims to find new therapeutic targets for preventing and treating these conditions.
Alzheimer's Diseaseblood-brain barrierlung organoidspathogen responseneutrophil dynamics
Research Aims
3AIM 01Investigate the impact of pathogens on blood-brain barrier function in Alzheimer's disease.
AIM 02Develop a vascularized human lung organoid model to study lung injury and repair.
AIM 03Examine the roles of neutrophil subpopulations in inflammation and tissue repair following lung injury.
Skills the Lab Values
cell cultureiPSC technologyanimal models3D organoid generationflow cytometryWestern blotRNA sequencingcomputational biologymicroscopyCRISPR
Output against the department
Publications335top 17% of dept.70th of 402
this lab
most publishedleast published
Citations17ktop 26% of dept.103rd of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.