Seattle University · ChemistryWhidbey Microbiome Lab
Christopher Whidbey · Seattle, Washington
Research Focus
Dr. Christopher Whidbey's lab at Seattle University focuses on understanding the vaginal microbiome and its influence on women's health, particularly in relation to bacterial vaginosis and preterm birth. Using a technique called activity-based protein profiling, the lab studies specific enzymes within the microbiome to identify those associated with healthy conditions versus those linked to disease. This research aims to inform the development of new probiotics or drug therapies that could improve vaginal health and prevent reproductive health issues.
vaginal microbiomebacterial vaginosisprobioticsenzyme activitychemical proteomics
Research Aims
4AIM 01Test the activity of glycogen degrading enzymes in healthy and bacterial vaginosis conditions.
AIM 02Identify enzymes that influence the vaginal microbiome composition.
AIM 03Develop therapeutic strategies based on enzymatic activity insights.
AIM 04Determine the prevalence and activity of microbial proteases in various vaginal health states.
Skills the Lab Values
activity-based protein profilingmass spectrometrySDS-PAGEfluorescent taggingbiotinylation
Output against the department
Publications29bottom 6% of dept.204th of 216
this lab
most publishedleast published
Citations1.1kbottom 7% of dept.200th of 216
this lab
most citedleast cited
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