RUThe Rockefeller University · Biology
Fuchs Regeneration Lab
Elaine Fuchs · New York, New York
Research Focus
Dr. Elaine Fuchs' lab at Rockefeller University studies how skin stem cells contribute to tissue growth, maintenance, and healing. The research focuses on understanding how these cells communicate with their environment and respond to signals, which is crucial for maintaining healthy skin and informing regenerative medicine. By investigating the mechanisms of stem cell behavior and their role in diseases like cancer, the lab aims to develop new therapeutic strategies for skin-related disorders.
stem cellsskin developmenttissue regenerationcancer biologycell communicationepidermal dynamicsmechanical forceschromatin remodelinginflammatory responseregenerative medicine
Research Aims
4AIM 01Map the interactions of skin progenitor cells with their neighbors to understand stem cell behavior.
AIM 02Identify signaling pathways that regulate epidermal stem cell dynamics and differentiation.
AIM 03Investigate the mechanisms of how stem cells eliminate malfunctioning cells to maintain tissue integrity.
AIM 04Study the chromatin dynamics governing stem cell fate decisions during homeostasis and after injury.
Skills the Lab Values
cell culturemouse modelsflow cytometryRNA sequencingCRISPRgene expression analysischromatin immunoprecipitationtissue sectioningimmunofluorescence microscopytransgenic mouse techniques
Output against the department
Publications526top 7% of dept.75th of 1,033
this lab
most publishedleast published
Citations90ktop 1% of dept.15th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.