Augusta University · PhysiologyMohamed Lab
Riyaz Mohamed · Augusta, Georgia
Research Focus
Dr. Riyaz Mohamed's lab at Augusta University focuses on understanding polycystic kidney disease (PKD), a genetic disorder that causes the formation of numerous cysts in the kidneys, ultimately leading to kidney failure. The lab is particularly interested in a molecule called netrin-1, which appears to play a role in promoting cyst growth. By studying how netrin-1 influences kidney cells and immune responses, the lab aims to identify new therapeutic targets to treat PKD more effectively and safely.
polycystic kidney diseasenetrin-1cyst growthkidney pathologymacrophage polarization
Research Aims
3AIM 01Investigate how netrin-1 contributes to cell proliferation in cystic epithelial cells.
AIM 02Explore the role of netrin-1 in macrophage polarization and cyst growth.
AIM 03Identify the downstream signaling pathways activated by netrin-1 in polycystic kidney disease.
Skills the Lab Values
cell culturemolecular biology techniquesanimal modelsimmunoassayspharmacological treatment assessment
Output against the department
Publications80bottom 19% of dept.231st of 286
this lab
most publishedleast published
Citations1.5kbottom 7% of dept.265th of 286
this lab
most citedleast cited
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