The University of Texas at Dallas · ChemistryCyclic Innovation Lab
Rudi Fasan · Richardson, Texas
Research Focus
Dr. Rudi Fasan's lab at the University of Texas Dallas focuses on creating new methods for discovering and synthesizing bioactive molecules, especially cyclic peptides, which can modulate biomolecular interactions with high precision. Their innovative approaches combine chemistry and biology to develop new catalysts and platforms that streamline drug discovery processes and enhance our understanding of complex biological systems.
chemoenzymatic synthesismacrocyclic peptidesbiocatalysisasymmetric synthesisnatural productsdrug discoveryprotein-protein interactionshemoproteinsstereoselective reactionshigh-throughput screening
Research Aims
5AIM 01Develop novel methods for synthesizing complex macrocyclic peptides
AIM 02Create biocatalytic systems for asymmetric synthesis
AIM 03Streamline discovery of peptide modulators targeting membrane proteins
AIM 04Investigate the use of engineered hemoproteins for stereoselective reactions
AIM 05Enhance drug discovery processes through novel methodologies.
Skills the Lab Values
PCRprotein purificationcell cultureenzyme assayspeptide synthesishigh-throughput screeningcomputational designbiocatalysisspectroscopychromatography
Output against the department
Publications192bottom 45% of dept.118th of 216
this lab
most publishedleast published
Citations8.5kbottom 47% of dept.114th of 216
this lab
most citedleast cited
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