Brown University · BiochemistryAlzheimer's Biomarker Discovery Lab
Jill Kreiling · Providence, Rhode Island
Research Focus
Dr. Jill Kreiling's lab at Brown University is focused on developing non-invasive biomarkers for Alzheimer's disease and related disorders. The team is exploring salivary extracellular vesicles to identify RNA and protein patterns that help predict the risk of developing these neurodegenerative diseases. Their work aims to create accessible testing methods that could lead to earlier interventions for patients before serious symptoms arise.
Alzheimer's Diseasebiomarkerssalivary extracellular vesiclesneurodegenerative disordersRNAproteomics
Research Aims
3AIM 01Identify RNA and protein biomarkers in salivary extracellular vesicles for early diagnosis of Alzheimer's Disease.
AIM 02Extend research to include biomarkers in salivary extracellular vesicles from patients with related disorders such as FTD, PD, DLB, and ALS.
AIM 03Track changes in salivary extracellular vesicle composition in cognitively normal individuals over time to study progression towards Alzheimer's disease.
Skills the Lab Values
PCRRNA extractionprotein assayscell culturemolecular cloningnext-generation sequencingbioinformaticsdata analysissalivary EV isolation
Output against the department
Publications58bottom 11% of dept.359th of 402
this lab
most publishedleast published
Citations3.5kbottom 17% of dept.334th of 402
this lab
most citedleast cited
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