University of Virginia-Main Campus · NeuroscienceThe RNA Pathway Lab
Lulu Jiang · Charlottesville, Virginia
Research Focus
Dr. Lulu Jiang's lab focuses on understanding the mechanisms behind Alzheimer's disease, particularly how RNA modifications affect the disease's progression. They study how tau protein aggregates can alter RNA methylation, leading to neuronal dysfunction. The lab employs innovative techniques to explore new therapeutic strategies that could help in treating Alzheimer's and related disorders.
Alzheimer's diseasetau pathologyRNA modificationm6A methylationneurodegeneration
Research Aims
3AIM 01Investigate tau-induced alterations in RNA modification in Alzheimer's disease.
AIM 02Characterize the role of m6A RNA methylation in neuronal dysfunction.
AIM 03Evaluate therapeutic interventions targeting RNA methylation in Alzheimer's models.
Skills the Lab Values
m6A DART-seq3D neuron-glial assembloidsmouse modelsRNA sequencingprotein translation analysis
Output against the department
Publications141bottom 49% of dept.341st of 671
this lab
most publishedleast published
Citations3.1kbottom 23% of dept.518th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.