University of South Florida · PhysiologyDiabetic Kidney Research Lab
Alexander Staruschenko · Tampa, Florida
Research Focus
Dr. Alexander Staruschenko's lab at the University of South Florida focuses on understanding sex-related differences in diabetic kidney disease (DKD). They study the mechanisms behind how diabetes affects kidney function differently in men and women, using a special rat model of type 2 diabetic nephropathy. Their goal is to identify molecular pathways that could lead to more effective, tailored treatments for diabetic kidney disease.
diabetic kidney diseasecGAS-STING pathwaysexual dimorphisminflammationdrug targetingtype 2 diabeteschronic kidney diseaserenal injurypodocytopathy
Research Aims
3AIM 01Explore functional and structural differences in diabetic nephropathy between male and female rats.
AIM 02Identify critical pathways contributing to sexual dimorphism in diabetic kidney disease.
AIM 03Investigate the role of the cGAS-STING signaling pathway in renal inflammation and injury.
Skills the Lab Values
animal modelsin vivo studiesex vivo studiesbiochemical assaysmolecular biology techniquesWestern blotRNA sequencingpathway analysisdata interpretation
Output against the department
Publications433top 8% of dept.23rd of 286
this lab
most publishedleast published
Citations6.6ktop 50% of dept.142nd of 286
this lab
most citedleast cited
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