UAUniversity of Arkansas · Chemistry
Lysine Modification and Metabolism Unit
Chenguang Fan · Fayetteville, Arkansas
Research Focus
Dr. Chenguang Fan's lab focuses on a new type of protein modification called lysine aminoacylation, which plays an important role in human metabolism and disease. By studying this process, the lab aims to better understand how certain enzymes in our cells are modified and how these modifications affect cell function. The research also involves developing advanced tools and techniques to study these modifications, with implications for understanding and treating human diseases.
lysine aminoacylationmetabolic enzymespost-translational modificationcellular metabolismgenetic code expansion
Research Aims
3AIM 01Determine the specificity of aminoacyl-tRNA synthetases for lysine aminoacylation.
AIM 02Develop orthogonal translation systems for studying lysine aminoacylation.
AIM 03Investigate the role of lysine aminoacylation in regulating cellular metabolism.
Skills the Lab Values
cell culturegenetic code expansion techniquesfluorescence-activated cell sorting (FACS)protein purificationenzyme activity assays
Output against the department
Publications78bottom 15% of dept.184th of 216
this lab
most publishedleast published
Citations4.1kbottom 30% of dept.152nd of 216
this lab
most citedleast cited
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