Georgetown University · BiochemistryLevi Lab
Moshe Levi · Washington, District of Columbia
Research Focus
Dr. Moshe Levi's lab at Georgetown University studies how certain lipids and hormone receptors affect kidney health, especially in conditions like diabetes and obesity. They explore how the composition of these lipids can influence inflammation and mitochondrial function, which are critical for kidney disease progression. The lab uses advanced techniques to understand the underlying mechanisms of age-related kidney disease and how caloric restriction might help mitigate its effects.
kidney diseaseglycosphingolipidsdiabetesobesityinflammationestrogen related receptorsmitochondrial functioncaloric restrictionmouse models
Research Aims
4AIM 01Investigate the role of glycosphingolipids in diabetes-related kidney disease.
AIM 02Assess how inhibiting lipid synthesis affects kidney function in obesity and diabetes.
AIM 03Examine the influence of estrogen related receptors on age-related kidney health.
AIM 04Determine the relationship between lipid composition, inflammation, and kidney disease progression.
Skills the Lab Values
lipid profiling by LC-MS/MSimmunofluorescence microscopyflow cytometryRNA sequencingspatial transcriptomicselectron microscopyextracellular acidification measurementhigh-dimensional data analysisinducible gene expression
Output against the department
Publications298top 21% of dept.85th of 402
this lab
most publishedleast published
Citations20ktop 21% of dept.84th of 402
this lab
most citedleast cited
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