Columbia University in the City of New York · BiologyAlzheimer's Research and Biomarkers Lab
Andrew Franklin Teich · New York, New York
Research Focus
Dr. Andrew Teich's lab focuses on understanding how Alzheimer's Disease affects brain structure and function, particularly in elderly patients with normal pressure hydrocephalus. By examining brain tissue and cerebrospinal fluid from surgical patients, the lab investigates the role of immune responses in the brain and how they relate to cognitive decline. This research aims to identify biomarkers that could help predict outcomes in Alzheimer's patients, thereby improving clinical care.
Alzheimer's Diseasemicrogliacerebrospinal fluidproteomicsnormal pressure hydrocephalusbiopsyRNA sequencingcognitive decline
Research Aims
3AIM 01Characterize microglial changes in brain tissue from Alzheimer's patients.
AIM 02Correlate cerebrospinal fluid protein changes with microglial responses.
AIM 03Explore the predictive value of microglial responses for cognitive decline.
Skills the Lab Values
RNA sequencingbiological sample processingcerebrospinal fluid collectionbiopsy techniquesimmunohistochemistryproteomics analysisdata analysis in Rmicroscopystatistical analysis
Output against the department
Publications118bottom 42% of dept.594th of 1,033
this lab
most publishedleast published
Citations5.2kbottom 39% of dept.631st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.