UCUniversity of Cincinnati-Main Campus · Pharmacology
Microplastics and Cardiac Health Lab
Hong-Sheng Wang · Cincinnati, Ohio
Research Focus
Dr. Hong-Sheng Wang's research lab at the University of Cincinnati focuses on understanding how micro- and nanoplastics (tiny plastic particles) affect heart health. These particles are commonly found in the environment and can accumulate in the human body, potentially leading to serious heart problems. The lab conducts experiments using advanced models to explore how these plastics cause damage to heart cells and affect heart function. Their work aims to reveal critical information about the risks posed by these environmental contaminants to human cardiac health.
microplasticsnanoplasticscardiac toxicitycardiovascular healthheart diseaseoxidative stressmitochondrial dysfunctionenvironmental pollutants
Research Aims
3AIM 01Investigate how micro- and nanoplastics impact cardiac physiology and function.
AIM 02Assess the damage caused by micro- and nanoplastics in the context of heart ischemia injury.
AIM 03Explore the mechanisms of cardiac toxicity induced by micro- and nanoplastics, focusing on mitochondrial dysfunction and autophagy.
Skills the Lab Values
animal modelscell cultureinducible pluripotent stem cellscardiomyocyte assaysanalytical chemistryin vivo studiesorganoid modelsimaging techniquesdata analysismechanistic studies