University of Washington-Seattle Campus · PharmacologyThe Adolescent NeuroLab
Nephi Stella · Seattle, Washington
Research Focus
Dr. Nephi Stella's lab at the University of Washington studies how consuming cannabis, particularly THC, during adolescence affects brain development and behavior in adulthood. The team's research focuses on the impact of oral THC consumption through innovative gel formulations and aims to understand the long-term consequences on neural systems and behaviors, particularly in relation to reward and motivation. Their work highlights the need for more information on how adolescent cannabis use can lead to changes in the brain that may impair functioning later in life.
THCcannabidioladolescent brain developmentoral consumptionbehavioral impairmentneurotransmissionmesocorticolimbic systemgelatin formulations
Research Aims
3AIM 01Determine the impact of THC-E-gel on adult behavior resulting from adolescent consumption.
AIM 02Isolate effects of THC and CBD on neural activity in adult mice from adolescent use.
AIM 03Define molecular and circuit changes in the brain due to THC and CBD consumption during adolescence.
Skills the Lab Values
mouse modelsoral drug administrationbehavioral assayselectrophysiologyimmunohistochemistryfiber photometrydata collection and analysisexperimental designmolecular biology techniques
Output against the department
Publications218top 39% of dept.178th of 462
this lab
most publishedleast published
Citations15ktop 25% of dept.117th of 462
this lab
most citedleast cited
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