UTMThe University of Texas MD Anderson Cancer Center · Biology
Bladder Cancer Molecular Dynamics Lab
Bogdan A Czerniak · Houston, Texas
Research Focus
Dr. Bogdan A Czerniak's lab focuses on understanding bladder cancer, a common and deadly disease. The research aims to identify how bladder cancer develops and evolves, particularly looking at the cellular changes that contribute to its severity and resistance to treatment. By characterizing the molecular mechanisms involved, the lab aims to develop new therapies to improve early detection and treatment outcomes for bladder cancer patients.
bladder cancercarcinogenesistherapeutic vulnerabilitiesmolecular profilingphenotypic plasticity
Research Aims
3AIM 01Investigate the evolution of bladder cancer from field effects to clinically aggressive disease.
AIM 02Characterize the role of luminal differentiation in tumor formation.
AIM 03Explore the plasticity between luminal and basal characteristics in response to interferon therapy.
Skills the Lab Values
molecular characterizationgene expression analysiscell culture techniquesbioinformaticsmolecular mappingtherapeutic response evaluationprotein analysisinterferon therapydata analysisstatistical modeling
Output against the department
Publications498top 8% of dept.85th of 1,033
this lab
most publishedleast published
Citations74ktop 2% of dept.18th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.