New York University · BiologyZebrafish Wound Healing and Neuronal Development Lab
Holger Knaut · New York, New York
Research Focus
Dr. Holger Knaut's lab at NYU School of Medicine focuses on understanding how skin repairs itself after injuries and how neuronal tissues migrate and split during development. They use zebrafish embryos for their research because these embryos are transparent, allowing for high-resolution imaging. By studying the molecular mechanisms behind wound healing and nerve formation, the lab aims to provide insights into potential treatments for skin disorders and neurological diseases.
wound healingneuronal developmentzebrafishGPCR signalingtissue migrationcell adhesionactomyosin contractionmechanotransductiontissue splitting
Research Aims
5AIM 01Identify the signaling pathways involved in skin wound detection and repair.
AIM 02Understand how skin layers cooperate to close wounds.
AIM 03Develop a physical model to study skin elasticity and healing processes.
AIM 04Investigate how attractant gradients guide tissue migration during neuronal development.
AIM 05Analyze cellular mechanics involved in the splitting of neuronal tissues.
Skills the Lab Values
Zebrafish embryologyImaging techniquesGenetic manipulationQuantitative microscopyCell cultureFlow cytometryComputational modelingBiophysicsTissue mechanics
Output against the department
Publications73bottom 21% of dept.818th of 1,033
this lab
most publishedleast published
Citations3.7kbottom 28% of dept.744th of 1,033
this lab
most citedleast cited
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