Wayne State University · ChemistryAllen Imaging Lab
Matthew J Allen · Detroit, Michigan
Research Focus
Dr. Matthew Allen's lab focuses on developing innovative imaging agents that can help visualize oxygen levels in the body, which is crucial for understanding diseases like cancer and kidney disorders. The lab is working on a new class of contrast agents that contain europium, a rare earth element, aiming to improve their delivery and effectiveness in medical imaging. This research has the potential to transform diagnostics and therapy for conditions associated with low oxygen levels.
MRIhypoxiacontrast agentseuropiumbioconjugationdrug deliverydendrimers
Research Aims
3AIM 01Study new derivatives of phosphonate complexes to enhance their properties.
AIM 02Investigate dendrimeric conjugates for improved systemic delivery of europium agents.
AIM 03Evaluate the toxicity and biodistribution of europium-containing complexes in animal models.
Skills the Lab Values
synthesis of phosphonate complexesmagnetic resonance imaging techniquesbiodistribution studies in micetoxicology assessmentsdata analysis using NMR spectroscopy
Output against the department
Publications11bottom 1% of dept.212th of 216
this lab
most publishedleast published
Citations12ktop 43% of dept.93rd of 216
this lab
most citedleast cited
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