University of Arizona · PharmacologyEstrogen Impact Lab
Roberta Eileen Brinton · Tucson, Arizona
Research Focus
Dr. Roberta Brinton's lab at the University of Arizona focuses on understanding how estrogen affects brain health, particularly during the transition to menopause. The research investigates the impact of aging and hormonal changes on the brain's energy systems and their implications for diseases like Alzheimer's. By studying these mechanisms, the lab aims to find ways to prevent or delay cognitive decline in aging women due to hormonal changes.
AgingAlzheimer's DiseaseEstrogenBioenergeticsWomen's HealthPerimenopauseNeurodegenerationMetabolic RegulationGene Expression
Research Aims
5AIM 01Investigate how estrogen regulates energy metabolism in the female brain.
AIM 02Determine the effects of estrogen loss on brain bioenergetics during aging.
AIM 03Explore the relationship between perimenopause and Alzheimer's disease risk.
AIM 04Develop biomarkers for early detection of Alzheimer's in perimenopausal women.
AIM 05Create strategies to maintain cognitive health in aging women.
Skills the Lab Values
Cell CultureMolecular Biology TechniquesAnimal ModelsBiochemical AssaysImaging TechniquesData AnalysisRNA IsolationPCRWestern BlottingFlow Cytometry
Output against the department
Publications2bottom 1% of dept.458th of 462
this lab
most publishedleast published
Citations2bottom 1% of dept.458th of 462
this lab
most citedleast cited
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