University of Rochester · NeuroscienceChronic Pain and Glymphatic Research Lab
Lauren M Hablitz · Rochester, New York
Research Focus
Dr. Lauren Hablitz's research focuses on understanding how our body's sleep-wake cycle affects pain, particularly chronic neuropathic pain. Her lab investigates the glymphatic system, which helps remove waste from the brain, and how it interacts with the immune system. By studying these connections, the lab aims to discover new, non-drug therapies to manage chronic pain, thereby improving overall health and quality of life.
chronic painglymphatic systemnociceptioncircadian rhythmsimmune responseneuroinflammationnon-pharmacological therapycytokine distributionsleep disorderspain management
Research Aims
3AIM 01Investigate how the glymphatic/lymphatic CSF switch changes during chronic pain development.
AIM 02Examine the role of the molecular clock in regulating CSF and cytokine distribution throughout the day.
AIM 03Explore the effects of time-restricted feeding on chronic pain and glymphatic function.
Skills the Lab Values
circadian rhythm analysisCSF sampling techniquesmouse modelsimmunohistochemistryflow cytometryRNA biochemistrybehavioral pain assaysmolecular clock assessmentsdata visualizationexperimental design
Output against the department
Publications39bottom 7% of dept.625th of 671
this lab
most publishedleast published
Citations3.6kbottom 27% of dept.491st of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.