Johns Hopkins University · BiologyLatent Viral Reservoir Research Lab
Aaron A Tobian · Baltimore, Maryland
Research Focus
Dr. Aaron A. Tobian's lab at Johns Hopkins University focuses on understanding how HIV-1 persists in the body despite treatment. They study the latent viral reservoir found in certain immune cells and how it is maintained or reactivated, especially in people undergoing kidney transplants. By examining the effects of different treatments on these reservoirs, the lab aims to develop strategies for potentially curing HIV.
HIV-1latent viral reservoirT-cell depletionkidney transplantationimmune response
Research Aims
3AIM 01Examine long-term dynamics of the HIV latent viral reservoir after kidney transplantation.
AIM 02Develop a tissue-specific atlas of the latent viral reservoir in lymph nodes and kidney before and after transplantation.
AIM 03Determine how different mechanisms contribute to the maintenance and re-establishment of the latent viral reservoir post-transplant.
Skills the Lab Values
PCRimmunofluorescencecell culturenext-generation sequencingdata analysismicroscopymulti-modal imagingflow cytometry
Output against the department
Publications559top 6% of dept.60th of 1,033
this lab
most publishedleast published
Citations21ktop 18% of dept.187th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.