Duke University · Mathematics & StatisticsInfluenza Antibody Modeling Lab
Cliburn C Chan · Durham, North Carolina
Research Focus
Dr. Cliburn C Chan's lab at Duke University focuses on developing computational models to better understand how the immune system responds to influenza viruses. By analyzing various datasets, the lab aims to create predictive models of antibody responses, which could lead to more effective vaccines against seasonal and pandemic influenza. They combine techniques from biostatistics and immunology to simulate how antibodies protect against infection, ultimately helping to advance vaccine development.
influenzaantibody modelingvaccine developmentcomputational biologyhumoral immune response
Research Aims
3AIM 01Develop protein language models to analyze antibody repertoires from human datasets.
AIM 02Create agent-based models to simulate immune responses during influenza infection.
AIM 03Construct dynamical systems models to examine antibody interactions with viral load and clearance.
Skills the Lab Values
computational modelingprotein language modelsagent-based modelingdata analysishigh-dimensional data visualization
Output against the department
Publications138bottom 26% of dept.97th of 131
this lab
most publishedleast published
Citations1.7kbottom 13% of dept.114th of 131
this lab
most citedleast cited
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