WMCWeill Medical College of Cornell University · Neuroscience
NeuroMito Lab
Hibiki Fujita · New York, New York
Research Focus
Dr. Hibiki Fujita's lab focuses on understanding the molecular mechanisms behind frontotemporal dementia and amyotrophic lateral sclerosis, specifically linked to a protein called CHCHD10. By studying how mutations in this protein lead to neurodegeneration and exploring potential therapies, the lab aims to develop new treatments for these challenging neurological diseases. Students in this lab will have the opportunity to engage in cutting-edge research on protein aggregation and mitochondrial dysfunction.
frontotemporal dementiaamyotrophic lateral sclerosisCHCHD10protein aggregationmitochondrial dysfunction
Research Aims
3AIM 01Elucidate the structural and molecular basis of CHCHD10 protein aggregation.
AIM 02Test the effects of antisense oligonucleotides on neuroprotection in mouse models.
AIM 03Investigate autophagy changes in neurodegenerative models to enhance the clearance of CHCHD10 aggregates.
Skills the Lab Values
biochemical techniquesmouse modelscell cultureRNA isolationwestern blottingimmunohistochemistrygenetic manipulationautophagy assessmentstructural biology methodsneurodegeneration modeling
Output against the department
Publications2bottom 1% of dept.664th of 671
this lab
most publishedleast published
Citations0bottom 1% of dept.670th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.