Ohio State University-Main Campus · ChemistryHIV RNA Packaging Research Group
Karin M Musier-Forsyth · Columbus, Ohio
Research Focus
Dr. Karin M. Musier-Forsyth's lab at Ohio State University focuses on understanding how the HIV-1 virus packages its RNA and how this process affects viral replication and function. The research investigates the role of different RNA structures produced from the virus's genetic material and how these structures interact with host factors during viral assembly and translation. Findings aim to inform the development of new therapies against HIV.
HIV-1RNA packagingretroviral proteins viral replicationtherapeutics
Research Aims
3AIM 01Identify and characterize HIV-1 RNA interactomes in vitro and in cells.
AIM 02Determine the effects of HIV-1 transcription start site choice on RNA modifications and dynamics.
AIM 03Investigate how HIV-1 TSS choice influences translation processes in vitro and in cells.
Skills the Lab Values
fluorescence microscopymass spectrometryin vitro RNA assaysmolecular cloningcell cultureRNA sequencinganalytical chemistrybioinformatics
Output against the department
Publications278top 41% of dept.88th of 216
this lab
most publishedleast published
Citations9.0kbottom 49% of dept.111th of 216
this lab
most citedleast cited
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